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| Description: | Des-2-(4-Isobutyl) 3-Ethoxy-2-methyl-3-oxo Ibuprofen is an intermediate in the synthesis of Hydroxy Ibuprofen (H943200), a metabolite of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. |
| Molecular Weight: | 264.32 |
| Molecular Formula: | C15H20O4 |
| Solubility: | Chloroform; Dichloromethane; Ethyl Acetate; Methanol |
| References: | Busson, M., et al. J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al. J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al. Clin. Pharmacokinet., 34, 101 (1998); Neunzig, I. et al. J. Biotechnol., 157, 417 (2012). |
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