Description: | Denitro 4-Methoxyphenyl Nimesulide is an intermediate in the synthesis of 4'-Hydroxy Nimesulide (H948560), the main metabolite of Nimesulide (N477500), an antiinflammatory agent which preferentially inhibits COX-2 over COX-1, suppresses chemical-induced carcinogenesis in mice and rats and inhibits LPS-induced TNF-alpha production. |
Molecular Weight: | 369.43 |
Molecular Formula: | C20H19NO4S |
References: | Pairet, M., et al. Inflamm. Res., 47, S93 (1998); Fukutake, M., et al. Carcinogenesis, 19, 1939 (1998); Okajima., E., et al. Cancer Res., 58, 3028 (1998); Azab, A., et al. Life Sci., 63, 323 (1998). |
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