D-Methionine 1,1-Dimethylethyl Ester Hydrochloride - CAS 1356447-69-2

Catalog:	BB060211
Product Name:	D-Methionine 1,1-Dimethylethyl Ester Hydrochloride
CAS:	1356447-69-2
Synonyms:	tert-Butyl D-methioninate hydrochloride; tert-butyl (2R)-2-amino-4-methylsulfanylbutanoate; hydrochloride

Technical Data

IUPAC Name:	tert-butyl (2R)-2-amino-4-methylsulfanylbutanoatehydrochloride
Description:	D-Methionine 1,1-Dimethylethyl Ester s a protected form of D-Methionine (M260550). D-Methionine is an isomer of L-Methionine (M260440), and is known to be a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
Molecular Weight:	241.78
Molecular Formula:	C9H20ClNO2S
Canonical SMILES:	CC(C)(C)OC(=O)C(CCSC)N.Cl
InChI:	InChI=1S/C9H19NO2S.ClH/c1-9(2,3)12-8(11)7(10)5-6-13-4/h7H,5-6,10H2,1-4H31H/t7-/m1./s1
InChI Key:	KZJQROCWHZGZBJ-OGFXRTJISA-N
References:	Campbell, K., et al. Hear. Res., 92, 103 (2007); Cloven, N., et al. Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al. Clin. Cancer Res., 14, 2161 (2008).

Complexity:	166
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	241.0903277
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	241.0903277
Rotatable Bond Count:	6
Topological Polar Surface Area:	77.6Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0