D-Glutamine tert-Butyl Ester Hydrochloride - CAS 422324-35-4

Catalog:	BB064466
Product Name:	D-Glutamine tert-Butyl Ester Hydrochloride
CAS:	422324-35-4
Synonyms:	D-Glutamine 1,1-Dimethylethyl Ester Hydrochloride; (R)-2-Amino-4-carbamoylbutyric Acid tert-Butyl Ester Hydrochloride

Technical Data

IUPAC Name:	tert-butyl (2R)-2,5-diamino-5-oxopentanoatehydrochloride
Description:	D-Glutamine tert-Butyl Ester Hydrochloride is a protected form of D-Glutamine G597295). D-Glutamine is an unnatural isomer of L-Glutamine (G597000) that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells.
Molecular Weight:	238.71
Molecular Formula:	C9H19ClN2O3
Canonical SMILES:	CC(C)(C)OC(=O)C(CCC(=O)N)N.Cl
InChI:	InChI=1S/C9H18N2O3.ClH/c1-9(2,3)14-8(13)6(10)4-5-7(11)12/h6H,4-5,10H2,1-3H3,(H2,11,12)1H/t6-/m1./s1
InChI Key:	ZEPNUNKDKQACNC-FYZOBXCZSA-N
References:	Almassy, R., et al. Nature, 323, 304 (1986); Frank, H., et al. J. Chromatog. B: Biomed. Sci. Appl., 224, 177 (1981); Jayme, D. Cytotechnology, 5, 15 (1991); Kagan, H. & Meister, A. Biochemistry, 5, 725 (1966); Levintow, L. & Meister, A. J. Am. Chem. Soc., 75, 3039 (1953); Raj, D., et al. Am. J. Phys. Endo. Metab., 280, E214 (2001); Varadi, M., et al. Biosens. Bioelect., 14, 335 (1999).

Complexity:	221
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	238.1084202
Formal Charge:	0
Heavy Atom Count:	15
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	238.1084202
Rotatable Bond Count:	6
Topological Polar Surface Area:	95.4Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0