Cyclopropylmethanesulfonyl Chloride - CAS 114132-26-2
Catalog: |
BB003299 |
Product Name: |
Cyclopropylmethanesulfonyl Chloride |
CAS: |
114132-26-2 |
Synonyms: |
cyclopropylmethanesulfonyl chloride; cyclopropylmethanesulfonyl chloride |
IUPAC Name: | cyclopropylmethanesulfonyl chloride |
Description: | Cyclopropylmethanesulfonyl Chloride (CAS# 114132-26-2) is used in the discovery of novel aminotetralines and aminochromanes as selective and competitive glycine transporter 1 (GlyT1) inhibitors. |
Molecular Weight: | 154.62 |
Molecular Formula: | C4H7ClO2S |
Canonical SMILES: | C1CC1CS(=O)(=O)Cl |
InChI: | InChI=1S/C4H7ClO2S/c5-8(6,7)3-4-1-2-4/h4H,1-3H2 |
InChI Key: | XJPMSKSCGIBWPC-UHFFFAOYSA-N |
Boiling Point: | 224.143 °C at 760 mmHg |
Density: | 1.449 g/cm3 |
Appearance: | Solid |
MDL: | MFCD10697744 |
LogP: | 2.04580 |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
US-2016083365-A1 | Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors | 20140919 |
US-2014275086-A1 | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy | 20130315 |
WO-2014140310-A1 | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy | 20130315 |
US-2014243312-A1 | Pyrrolo[2,3-d]pyrimidine derivatives | 20130222 |
US-2015225408-A1 | Pyrrolo[2,3-d]pyrimidine derivatives | 20130222 |
Complexity: | 163 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 153.9855283 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 153.9855283 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 42.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.1 |
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