Cyclobutylamine - CAS 2516-34-9
Catalog: |
BB018766 |
Product Name: |
Cyclobutylamine |
CAS: |
2516-34-9 |
Synonyms: |
cyclobutanamine |
IUPAC Name: | cyclobutanamine |
Description: | Cyclobutylamine (CAS# 2516-34-9) is a reactant in the preparation of imidazo[1,2-b]pyridazine derivatives as selective and orally available Mps1 (TTK) kinase inhibitors. |
Molecular Weight: | 71.12 |
Molecular Formula: | C4H9N |
Canonical SMILES: | C1CC(C1)N |
InChI: | InChI=1S/C4H9N/c5-4-2-1-3-4/h4H,1-3,5H2 |
InChI Key: | KZZKOVLJUKWSKX-UHFFFAOYSA-N |
Boiling Point: | 81.4 °C (752 mmHg) |
Density: | 0.833 g/cm3 |
Appearance: | Clear colorless to light yellow clear liquid |
MDL: | MFCD00001328 |
LogP: | 1.19790 |
GHS Hazard Statement: | H225 (97.87%): Highly Flammable liquid and vapor [Danger Flammable liquids] |
Precautionary Statement: | P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P370+P378, P403+P235, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021204175-A1 | Lipid nanoparticle composition | 20200409 |
WO-2021176049-A1 | Pyrazolopyrazines acting on cancers via inhibition of cdk12 | 20200306 |
WO-2021170658-A1 | Heterocyclic compounds for modulating nr2f6 | 20200225 |
WO-2021154997-A1 | Inhibitors of apol1 and methods of using same | 20200129 |
WO-2021154667-A1 | C3-SUBSTITUTED 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | 20200127 |
PMID | Publication Date | Title | Journal |
27305487 | 20160714 | Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor | Journal of medicinal chemistry |
22514076 | 20120528 | Searching for new cell-penetrating agents: hybrid cyclobutane-proline γ,γ-peptides | Organic & biomolecular chemistry |
21162138 | 20110101 | A 1H NMR and theoretical investigation of the conformations of some monosubstituted cyclobutanes | Magnetic resonance in chemistry : MRC |
20186912 | 20100406 | Synthesis of highly substituted cyclobutane fused-ring systems from N-vinyl beta-lactams through a one-pot domino process | Chemistry (Weinheim an der Bergstrasse, Germany) |
21577430 | 20090815 | Bis(2-cyclo-butyl-imino-methyl-4,6-dihydro-seleno-phenolato)zinc(II) | Acta crystallographica. Section E, Structure reports online |
Complexity: | 30.6 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 71.073499291 |
Formal Charge: | 0 |
Heavy Atom Count: | 5 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 71.073499291 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 26 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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