IUPAC Name: | 1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
Description: | Boc-L-4-trans-hydroxyproline methyl ester is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. |
Molecular Weight: | 245.27 |
Molecular Formula: | C11H19NO5 |
Canonical SMILES: | CC(C)(C)OC(=O)N1CC(CC1C(=O)OC)O |
InChI: | InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1 |
InChI Key: | MZMNEDXVUJLQAF-SFYZADRCSA-N |
Boiling Point: | 335.2±42.0 °C at 760 mmHg |
Melting Point: | 96 °C |
Purity: | >95% by GC |
Density: | 1.2±0.1 g/cm3 |
Appearance: | White Powder |
Storage: | Store at 2-8 °C |
MDL: | MFCD00076981 |
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Related Functional Groups
Carbonyl Compounds
Pyrrolidines
(Racemic trans)-1-tert-butyl 3-methyl 4-(2-Chloro-5-methylpyridin-3-yl)pyrrolidine-1,3-dicarboxylate
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