(-)-α-Bisabolol - CAS 23089-26-1
Catalog: |
BB017920 |
Product Name: |
(-)-α-Bisabolol |
CAS: |
23089-26-1 |
Synonyms: |
(-)-alpha-Bisabolol; alpha-Bisabolol; Kamillosan; Levomenol |
IUPAC Name: | (2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol |
Description: | (-)-α-Bisabolol is a monocyclic sesquiterpene alcohol found in various plants and mainly in Matricaria chamomilla, which exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol has neuroprotective effects, can attenuate nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. |
Molecular Weight: | 222.37 |
Molecular Formula: | C15H26O |
Canonical SMILES: | CC1=CCC(CC1)C(C)(CCC=C(C)C)O |
InChI: | InChI=1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1 |
InChI Key: | RGZSQWQPBWRIAQ-CABCVRRESA-N |
Boiling Point: | 314.5±11.0 °C at 760 mmHg |
Flash Point: | 112°C |
Purity: | ≥ 90 % |
Density: | 0.922 g/cm3 |
Appearance: | Liquid |
LogP: | 4.23020 |
Refractive Index: | n20/D 1.496 |
GHS Hazard Statement: | H317 (34.72%): May cause an allergic skin reaction [Warning Sensitization, Skin] |
Precautionary Statement: | P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
DE-202021002752-U1 | Functionalized pieces of ice | 20210824 |
CN-113456626-A | Xanthine oxidase inhibitor and screening method and application thereof | 20210816 |
CN-113425649-A | Sunscreen synergistic composition, cosmetic composition and preparation method thereof | 20210812 |
CN-113456571-A | PDRN-containing repairing and regenerating composition and preparation method thereof | 20210802 |
CN-113462148-A | High-performance plastic packaging bag | 20210802 |
PMID | Publication Date | Title | Journal |
30088836 | 20181001 | Protective effects of α-bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced myocardial infarction: In vivo and in vitro evidences | Journal of biochemical and molecular toxicology |
23571415 | 20130601 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
22981002 | 20121201 | An untargeted metabolomic approach in the chemotaxonomic assessment of two Salvia species as a potential source of α-bisabolol | Phytochemistry |
22867794 | 20121101 | Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis | Archives of biochemistry and biophysics |
23074916 | 20120901 | Chemical composition and antiphytoviral activity of essential oil of Micromeria graeca | Natural product communications |
Complexity: | 284 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 2 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 222.198365449 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 222.198365449 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 20.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.8 |
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