Bis(4-hydroxyphenyl)methane - CAS 620-92-8

Catalog:	BB031412
Product Name:	Bis(4-hydroxyphenyl)methane
CAS:	620-92-8
Synonyms:	4-[(4-hydroxyphenyl)methyl]phenol

Technical Data

IUPAC Name:	4-[(4-hydroxyphenyl)methyl]phenol
Description:	Bis(4-hydroxyphenyl)methane (CAS# 620-92-8) is a bisphenol derivative with antioxidant activities. Bisphenol F has been reported to exhibit estrogen agonistic properties.
Molecular Weight:	200.23
Molecular Formula:	C13H12O2
Canonical SMILES:	C1=CC(=CC=C1CC2=CC=C(C=C2)O)O
InChI:	InChI=1S/C13H12O2/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h1-8,14-15H,9H2
InChI Key:	PXKLMJQFEQBVLD-UHFFFAOYSA-N
Boiling Point:	390 °C at 760 mmHg
Melting Point:	162-164 °C
Flash Point:	192.9°C
Purity:	> 99.0 % (GC)
Density:	1.208 g/cm³
Solubility:	Soluble in ethanol, ether, chloroform, alkali
Appearance:	White powder
Storage:	Sealed in dry. Room temperature.
Decomposition:	When heated to decomposition it emits acrid smoke and irritating fumes
MDL:	MFCD00002385
LogP:	2.68860
Refractive Index:	1.6110 (estimate)
Stability:	Stable under recommended storage conditions
Vapor Pressure:	3.7X10-7 mm Hg at 25 °C (est)

GHS Hazard Statement:	H315 (81.48%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501
Signal Word:	Danger

Publication Number	Title	Priority Date
EP-3786211-A1	Curable composition and cured composition prepared therefrom	20200228
US-10961208-B1	Product of glycidyl ether of a mono or polyhydric phenol	20191224
EP-3842466-A1	Product of glycidyl ether of a mono or polyhydric phenol, epoxy resin composition, and process for producing product of glycidyl ether of a mono or polyhydric phenol	20191224
WO-2021127128-A1	Two part curable compositions	20191220
WO-2021125137-A1	Polyester resin and method for producing polyester resin	20191218

PMID	Publication Date	Title	Journal
34147605	20211010	Bisphenol F promotes the secretion of pro-inflammatory cytokines in macrophages by enhanced glycolysis through PI3K-AKT signaling pathway	Toxicology letters
34019995	20210801	Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells	Reproductive toxicology (Elmsford, N.Y.)
33865937	20210601	Bisphenol F and bisphenol S promote lipid accumulation and adipogenesis in human adipose-derived stem cells	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
34023961	20210522	Low doses of BPF-induced hypertrophy in cardiomyocytes derived from human embryonic stem cells via disrupting the mitochondrial fission upon the interaction between ERβ and calcineurin A-DRP1 signaling pathway	Cell biology and toxicology
33476716	20210401	Transcriptomic\xa0pathway\xa0and\xa0benchmark dose analysis of Bisphenol A, Bisphenol S, Bisphenol F, and 3,3',5,5'-Tetrabromobisphenol A in H9 human embryonic stem cells	Toxicology in vitro : an international journal published in association with BIBRA

Complexity:	157
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	200.083729621
Formal Charge:	0
Heavy Atom Count:	15
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	200.083729621
Rotatable Bond Count:	2
Topological Polar Surface Area:	40.5 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.9