Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane - CAS 6976-37-0
Catalog: |
BB033961 |
Product Name: |
Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane |
CAS: |
6976-37-0 |
Synonyms: |
2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol; 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol |
IUPAC Name: | 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol |
Description: | BIS-TRIS is a commonly used buffering agent that exhibits only a very small shift in dissociation constant. |
Molecular Weight: | 209.24 |
Molecular Formula: | C8H19NO5 |
Canonical SMILES: | C(CO)N(CCO)C(CO)(CO)CO |
InChI: | InChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
InChI Key: | OWMVSZAMULFTJU-UHFFFAOYSA-N |
Boiling Point: | ~466.18 °C at 760 mmHg (Predicted) |
Melting Point: | 102-105 °C |
Purity: | ≥ 99 % |
Density: | 1.3 g/cm3 (Predicted) |
Solubility: | Soluble in water (209.2 g/L) at 20 °C. |
Appearance: | White to off-white solid |
MDL: | MFCD00002853 |
LogP: | -3.01130 |
GHS Hazard Statement: | H315 (68.72%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113462673-A | Method for preparing protein of totipotent nuclease | 20210824 |
CN-113425844-A | Drug intervention target of keloid and application thereof | 20210709 |
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PMID | Publication Date | Title | Journal |
23896426 | 20130901 | Immobilized metal affinity chromatography and human serum proteomics | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
22922065 | 20121102 | The structural domains of Pseudomonas aeruginosa phosphorylcholine phosphatase cooperate in substrate hydrolysis: 3D structure and enzymatic mechanism | Journal of molecular biology |
22627968 | 20120721 | Using the flexible ligand bis(2-hydroxyethyl)amino-tris (hydroxymethyl)methane ('bis-tris') to access a family of 3d-4f Mn(III)4Ln4 complexes | Dalton transactions (Cambridge, England : 2003) |
22421417 | 20120615 | Temperature-modulated adsorption of poly(N-isopropylacrylamide)-grafted ferritin on solid substrate | Colloids and surfaces. B, Biointerfaces |
22094831 | 20120601 | Tungsten-induced denaturation and aggregation of epoetin alfa during primary packaging as a cause of immunogenicity | Pharmaceutical research |
Complexity: | 125 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 209.12632271 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 5 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 209.12632271 |
Rotatable Bond Count: | 8 |
Topological Polar Surface Area: | 104 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -3.3 |
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