Azido-PEG8-amine - CAS 857891-82-8
Catalog: |
BB037723 |
Product Name: |
Azido-PEG8-amine |
CAS: |
857891-82-8 |
Synonyms: |
O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine |
IUPAC Name: | 2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
Description: | Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 438.52 |
Molecular Formula: | C18H38N4O8 |
Canonical SMILES: | C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N |
InChI: | InChI=1S/C18H38N4O8/c19-1-3-23-5-7-25-9-11-27-13-15-29-17-18-30-16-14-28-12-10-26-8-6-24-4-2-21-22-20/h1-19H2 |
InChI Key: | ZSFGTBJYBWJOLZ-UHFFFAOYSA-N |
Purity: | ≥90% |
Appearance: | Colorless or Light Yellowish Liquid |
Storage: | Store at 2-8°C |
LogP: | 0.54126 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2021174983-A1 | Compositions for the filling of high aspect ratio vertical interconnect access (via) holes | 20191204 |
WO-2020139807-A2 | Nanocapsules for the delivery of cell modulating agents | 20181223 |
EP-3898978-A2 | Nanocapsules for the delivery of cell modulating agents | 20181223 |
US-2021322331-A1 | Nanocapsules for the delivery of cell modulating agents | 20181223 |
US-2021101930-A1 | Methods of generating nanoarrays and microarrays | 20180404 |
Complexity: | 376 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 438.26896418 |
Formal Charge: | 0 |
Heavy Atom Count: | 30 |
Hydrogen Bond Acceptor Count: | 11 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 438.26896418 |
Rotatable Bond Count: | 26 |
Topological Polar Surface Area: | 114 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1 |
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