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| IUPAC Name: | 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetic acid |
| Description: | N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units. N33-TEG-COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
| Molecular Weight: | 277.27 |
| Molecular Formula: | C10H19N3O6 |
| Canonical SMILES: | C(COCCOCCOCCOCC(=O)O)N=[N+]=[N-] |
| InChI: | InChI=1S/C10H19N3O6/c11-13-12-1-2-16-3-4-17-5-6-18-7-8-19-9-10(14)15/h1-9H2,(H,14,15) |
| InChI Key: | YHTABJLSZLHRFV-UHFFFAOYSA-N |
| Purity: | ≥95% |
| Density: | 0.750-0.850 g/mL at 20°C |
| Solubility: | Soluble in DMSO, Water |
| Appearance: | Liquid |
| Storage: | Store at 2-8°C |
| LogP: | -0.09954 |
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Carbonyl Compounds
1-{2-[(3-Methoxypropyl)amino]-4-methyl-1,3-thiazol-5-yl}ethanone hydrochloride
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