Azido-PEG3-acid - CAS 1056024-94-2
Catalog: |
BB001676 |
Product Name: |
Azido-PEG3-acid |
CAS: |
1056024-94-2 |
Synonyms: |
Azide-PEG3-Carboxylic acid;N3-PEG3-COOH; Azido-PEG3-C2-acid; N3-PEG3-CH2CH2COOH; Azido-PEG3-propionic acid; 12-Azido-4,7,10-trioxadodecanoic acid; Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]- |
Application: |
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. |
Related CAS: | 1167575-20-3 (polymer)
|
IUPAC Name: | 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoic acid |
Description: | Azido-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 247.25 |
Molecular Formula: | C9H17N3O5 |
Canonical SMILES: | C(COCCOCCOCCN=[N+]=[N-])C(=O)O |
InChI: | InChI=1S/C9H17N3O5/c10-12-11-2-4-16-6-8-17-7-5-15-3-1-9(13)14/h1-8H2,(H,13,14) |
InChI Key: | VWJGWKZZFZMGGY-UHFFFAOYSA-N |
Purity: | ≥95% |
Solubility: | Soluble in DMSO (10 mm) |
Appearance: | Colorless Liquid |
Storage: | Store at 2-8°C, keep in dry and avoid sunlight |
LogP: | -0.71 |
Publication Number | Title | Priority Date |
WO-2020163170-A1 | Trapping-free parp inhibitors | 20190205 |
WO-2020073345-A1 | Conjugation linkers containing 2,3-diaminosuccinyl group | 20181012 |
EP-3867250-A1 | Conjugation linkers containing 2,3-diaminosuccinyl group | 20181012 |
KR-20210076056-A | Conjugation linker containing 2,3-diaminosuccinyl group | 20181012 |
WO-2020006722-A1 | Cross-linked pyrrolobenzodiazepine dimer (pbd) derivative and its conjugates | 20180705 |
Complexity: | 243 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 247.11682065 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 247.11682065 |
Rotatable Bond Count: | 12 |
Topological Polar Surface Area: | 79.4 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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