Azelaic acid - CAS 123-99-9
Catalog: |
BB005779 |
Product Name: |
Azelaic acid |
CAS: |
123-99-9 |
Synonyms: |
Finacea; Anchoic acid; Azelex; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Skinoren; 1,9-Nonanedioic acid; Heptanedicarboxylic acid; n-Nonanedioic acid; AZA |
Application: |
Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals. |
IUPAC Name: | nonanedioic acid |
Description: | Azelaic acid is a naturally occurring saturated binary carboxylic acid containing nine carbon atoms, which is an important medium and long chain dibasic acid. Azelaic acid has been used in cosmetics for a long time. It has the function of inhibiting excessive secretion of oil, removing acne and freckles, and whitening skin, and it is very safe. |
Molecular Weight: | 188.22 |
Molecular Formula: | C9H16O4 |
Canonical SMILES: | C(CCCC(=O)O)CCCC(=O)O |
InChI: | InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13) |
InChI Key: | BDJRBEYXGGNYIS-UHFFFAOYSA-N |
Boiling Point: | 286°C at 100 mmHg |
Melting Point: | 98°C |
Flash Point: | 210 °C (closed cup) |
Purity: | >95% |
Density: | 1.029 g/cm3 |
Solubility: | Soluble in DMSO |
Appearance: | White Powder |
Storage: | Store at RT |
MDL: | MFCD00004432 |
LogP: | 1.88630 |
Quality Standard: | Cosetic Grade |
Refractive Index: | 1.4303 |
Vapor Pressure: | 0.00000001 [mmHg] |
GHS Hazard Statement: | H315 (47.96%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
EP-3763769-A1 | Method for preparing copolyamide resin and copolyamide hot-melt yarn | 20201109 |
US-10934384-B1 | Polyurethane elastomer compositions, and processes thereof | 20200909 |
US-10934385-B1 | Polyurethane elastomers, bio-additive foam compositions | 20200909 |
US-10980756-B1 | Methods of treatment | 20200316 |
US-11028217-B1 | Thermoplastic polyurethane compositions comprising nitro-substituted polyester diols | 20200313 |
PMID | Publication Date | Title | Journal |
22898471 | 20130701 | Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression | Journal of affective disorders |
23571415 | 20130601 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
22920095 | 20121201 | Newer approaches to the treatment of acne vulgaris | American journal of clinical dermatology |
22849351 | 20121001 | Management of acne scarring, part II: a comparative review of non-laser-based, minimally invasive approaches | American journal of clinical dermatology |
22749315 | 20120901 | SOS - too many signals for systemic acquired resistance? | Trends in plant science |
Complexity: | 147 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 188.10485899 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 188.10485899 |
Rotatable Bond Count: | 8 |
Topological Polar Surface Area: | 74.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.6 |
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