Azelaic acid - CAS 123-99-9

Catalog:	BB005779
Product Name:	Azelaic acid
CAS:	123-99-9
Synonyms:	Finacea; Anchoic acid; Azelex; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Skinoren; 1,9-Nonanedioic acid; Heptanedicarboxylic acid; n-Nonanedioic acid; AZA
Application:	Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals.

Technical Data

IUPAC Name:	nonanedioic acid
Description:	Azelaic acid is a naturally occurring saturated binary carboxylic acid containing nine carbon atoms, which is an important medium and long chain dibasic acid. Azelaic acid has been used in cosmetics for a long time. It has the function of inhibiting excessive secretion of oil, removing acne and freckles, and whitening skin, and it is very safe.
Molecular Weight:	188.22
Molecular Formula:	C9H16O4
Canonical SMILES:	C(CCCC(=O)O)CCCC(=O)O
InChI:	InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChI Key:	BDJRBEYXGGNYIS-UHFFFAOYSA-N
Boiling Point:	286°C at 100 mmHg
Melting Point:	98°C
Flash Point:	210 °C (closed cup)
Purity:	>95%
Density:	1.029 g/cm3
Solubility:	Soluble in DMSO
Appearance:	White Powder
Storage:	Store at RT
MDL:	MFCD00004432
LogP:	1.88630
Quality Standard:	Cosetic Grade
Refractive Index:	1.4303
Vapor Pressure:	0.00000001 [mmHg]

GHS Hazard Statement:	H315 (47.96%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362
Signal Word:	Warning

Publication Number	Title	Priority Date
EP-3763769-A1	Method for preparing copolyamide resin and copolyamide hot-melt yarn	20201109
US-10934384-B1	Polyurethane elastomer compositions, and processes thereof	20200909
US-10934385-B1	Polyurethane elastomers, bio-additive foam compositions	20200909
US-10980756-B1	Methods of treatment	20200316
US-11028217-B1	Thermoplastic polyurethane compositions comprising nitro-substituted polyester diols	20200313

PMID	Publication Date	Title	Journal
22898471	20130701	Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression	Journal of affective disorders
23571415	20130601	Structure-based identification of OATP1B1/3 inhibitors	Molecular pharmacology
22920095	20121201	Newer approaches to the treatment of acne vulgaris	American journal of clinical dermatology
22849351	20121001	Management of acne scarring, part II: a comparative review of non-laser-based, minimally invasive approaches	American journal of clinical dermatology
22749315	20120901	SOS - too many signals for systemic acquired resistance?	Trends in plant science

Complexity:	147
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	188.10485899
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	188.10485899
Rotatable Bond Count:	8
Topological Polar Surface Area:	74.6 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.6