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| IUPAC Name: | (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid |
| Description: | Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. |
| Molecular Weight: | 304.47 |
| Molecular Formula: | C20H32O2 |
| Canonical SMILES: | CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
| InChI: | InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- |
| InChI Key: | YZXBAPSDXZZRGB-DOFZRALJSA-N |
| Boiling Point: | 169-171 °C at 0.1 mmHg |
| Melting Point: | -49°C |
| Flash Point: | 336.3°C |
| Purity: | 98 % |
| Density: | 0.922 g/cm3 |
| Appearance: | Clear to slight yellow liquid |
| Storage: | -20°C |
| MDL: | MFCD00004417 |
| LogP: | 6.21670 |
| Refractive Index: | 1.4872 |
| Stability: | Stable under normal temperatures and pressures. |
| Vapor Pressure: | 0.00000015 [mmHg] |
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2-(6-Ethyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
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