Anthranilamide - CAS 88-68-6
Catalog: |
BB039150 |
Product Name: |
Anthranilamide |
CAS: |
88-68-6 |
Synonyms: |
2-AMINOBENZAMIDE; Benzamide, 2-amino-; o-Aminobenzamide; 2-Carbamoylaniline; Aminobenzamide; Anthranilimidic acid |
IUPAC Name: | 2-aminobenzamide |
Description: | It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. |
Molecular Weight: | 136.15 |
Molecular Formula: | C7H8N2O |
Canonical SMILES: | C1=CC=C(C(=C1)C(=O)N)N |
InChI: | InChI=1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10) |
InChI Key: | PXBFMLJZNCDSMP-UHFFFAOYSA-N |
Boiling Point: | 300 °C |
Melting Point: | 111-114 °C |
Purity: | 95 % |
Density: | 1.233 g/cm3 |
Solubility: | >20.4 [ug/mL] (The mean of the results at pH 7.4) |
Appearance: | Light brown to grey-brown crystal powder or flakes |
Storage: | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00007981 |
LogP: | 1.64920 |
Vapor Pressure: | 0.0000263 [mmHg] |
GHS Hazard Statement: | H302 (51.67%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
US-2020362044-A1 | Methods of Treating Cytokine Storm Infections, Including COVID-19, By Inhibiting CCR5/CCL5 (RANTES) Interaction, and Compositions for Practicing the Same | 20200427 |
US-2021032355-A1 | Methods of Treating Cytokine Storm Infections, Including COVID-19, By Inhibiting CCR5/CCL5 (RANTES) Interaction, and Compositions for Practicing the Same | 20200427 |
US-2021171646-A1 | Methods of Treating Cytokine Storm Infections, Including COVID-19, By Inhibiting CCR5/CCL5 (RANTES) Interaction, and Compositions for Practicing the Same | 20200427 |
US-2021189214-A1 | Antifreezing coolant composition not including glycol | 20191220 |
US-2021190790-A1 | Methods for quantitating extra-cellular vesicle surface markers, and compositions for practicing the same | 20191220 |
PMID | Publication Date | Title | Journal |
28274627 | 20170415 | Three-component, one-pot synthesis of anthranilamide Schiff bases bearing 4-aminoquinoline moiety as Mycobacterium tuberculosis gyrase inhibitors | Bioorganic & medicinal chemistry letters |
25159818 | 20141001 | Epigenetic therapy for Friedreich ataxia | Annals of neurology |
22764181 | 20120901 | Rationale for the development of 2-aminobenzamide histone deacetylase inhibitors as therapeutics for Friedreich ataxia | Journal of child neurology |
22722482 | 20120821 | Tetrahydroindazolone substituted 2-aminobenzamides as fluorescent probes: switching metal ion selectivity from zinc to cadmium by interchanging the amino and carbamoyl groups on the fluorophore | Organic & biomolecular chemistry |
22852777 | 20120817 | Pd-catalyzed benzylic C-H amidation with benzyl alcohols in water: a strategy to construct quinazolinones | The Journal of organic chemistry |
Complexity: | 136 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 136.063662883 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 136.063662883 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 69.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.4 |
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