Amino-PEG6-alcohol - CAS 39160-70-8
Catalog: |
BB023862 |
Product Name: |
Amino-PEG6-alcohol |
CAS: |
39160-70-8 |
Synonyms: |
17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol; H2N-PEG6-OH; 1-Aminohexaethylene Glycol |
Related CAS: | 933789-97-0 (polymer)
|
IUPAC Name: | 2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
Description: | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 281.35 |
Molecular Formula: | C12H27NO6 |
Canonical SMILES: | C(COCCOCCOCCOCCOCCO)N |
InChI: | InChI=1S/C12H27NO6/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h14H,1-13H2 |
InChI Key: | ICUIZKMGHRMMDZ-UHFFFAOYSA-N |
Boiling Point: | 388.0±37.0 °C at 760 mmHg |
Flash Point: | 188.5±26.5 °C |
Purity: | ≥95% |
Density: | 1.1±0.1 g/cm3 |
Solubility: | Soluble in DMSO (10 mm) |
Appearance: | Pale Yellow or Colorless Oily Matter |
Storage: | Store at 2-8°C |
LogP: | -2.80 |
Vapor Pressure: | 0.0±2.0 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
KR-102160377-B1 | Atorvastatin Derived HMG-CoA Reductase Degradation Inducing Compound | 20200325 |
US-11066391-B1 | Atorvastatin derived HMG-CoA reductase degradation inducing compound | 20200325 |
WO-2020163170-A1 | Trapping-free parp inhibitors | 20190205 |
WO-2020152067-A1 | Heterocyclic derivatives | 20190122 |
US-2019192668-A1 | Irak degraders and uses thereof | 20171226 |
Complexity: | 161 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 281.18383758 |
Formal Charge: | 0 |
Heavy Atom Count: | 19 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 281.18383758 |
Rotatable Bond Count: | 16 |
Topological Polar Surface Area: | 92.4 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -2.1 |
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