Amino-PEG4-alcohol - CAS 86770-74-3
Catalog: |
BB038063 |
Product Name: |
Amino-PEG4-alcohol |
CAS: |
86770-74-3 |
Synonyms: |
2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol; 1-Amino-3,6,9-Trioxaundecanyl-11-ol |
Related CAS: | 933789-97-0 (polymer)
|
IUPAC Name: | 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethanol |
Description: | Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 193.24 |
Molecular Formula: | C8H19NO4 |
Canonical SMILES: | C(COCCOCCOCCO)N |
InChI: | InChI=1S/C8H19NO4/c9-1-3-11-5-7-13-8-6-12-4-2-10/h10H,1-9H2 |
InChI Key: | ANOJXMUSDYSKET-UHFFFAOYSA-N |
Boiling Point: | 301.6±27.0 °C at 760 mmHg |
Flash Point: | 136.2±23.7 °C |
Purity: | ≥95% |
Density: | 1.1±0.1 g/cm3 |
Solubility: | Soluble in Water (50 mg/ml; 25875 mm; need ultrasonic) |
Appearance: | Pale Yellow Oily Matter |
Storage: | Store at 2-8°C |
MDL: | MFCD01752874 |
LogP: | -2.09 |
Vapor Pressure: | 0.0±1.4 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
KR-20210122708-A | HMG-CoA Reductase Degradation Inducing Compound | 20200330 |
WO-2021201577-A1 | Hmg-coa reductase degradation inducing compound | 20200330 |
WO-2021194318-A1 | Plk1 selective degradation inducing compound | 20200327 |
KR-102160377-B1 | Atorvastatin Derived HMG-CoA Reductase Degradation Inducing Compound | 20200325 |
US-11066391-B1 | Atorvastatin derived HMG-CoA reductase degradation inducing compound | 20200325 |
Complexity: | 92.2 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 193.13140809 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 193.13140809 |
Rotatable Bond Count: | 10 |
Topological Polar Surface Area: | 73.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.8 |
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