Amino-PEG3-propionic acid - CAS 784105-33-5
Catalog: |
BB036165 |
Product Name: |
Amino-PEG3-propionic acid |
CAS: |
784105-33-5 |
Synonyms: |
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid; H2N-PEG3-CH2CH2COOH |
Related CAS: | 1818294-41-5 (polymer) 196936-04-6 (polymer) |
IUPAC Name: | 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid |
Description: | Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 221.25 |
Molecular Formula: | C9H19NO5 |
Canonical SMILES: | C(COCCOCCOCCN)C(=O)O |
InChI: | InChI=1S/C9H19NO5/c10-2-4-14-6-8-15-7-5-13-3-1-9(11)12/h1-8,10H2,(H,11,12) |
InChI Key: | XUQZKSCQPMNDEY-UHFFFAOYSA-N |
Boiling Point: | 372.1±32.0 °C at 760 mmHg |
Purity: | ≥ 97.0 % |
Density: | 1.1±0.1 g/cm3 |
Solubility: | 10 mm in DMSO |
Appearance: | White powder |
Storage: | Store at -20 °C, keep in dry and avoid sunlight. |
LogP: | 0.16990 |
Precautionary Statement: | P261-P305+P351+P338 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021152186-A2 | Ccr8 antibodies for therapeutic applications | 20200626 |
WO-2021207086-A1 | Tem-1-targeted radioimmunoconjugates and uses thereof | 20200406 |
WO-2021194343-A1 | Reporter system for radionuclide imaging | 20200325 |
WO-2021195131-A1 | Fgfr3-targeted radioimmunoconjugates and uses thereof | 20200323 |
WO-2021168305-A1 | Designer peptides and proteins for the detection, prevention and treatment of coronavirus disease, 2019 (covid-19) | 20200219 |
Complexity: | 153 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 221.12632271 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 221.12632271 |
Rotatable Bond Count: | 11 |
Topological Polar Surface Area: | 91 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -3.9 |
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