Amino-PEG2-t-butyl ester - CAS 756525-95-8
Catalog: |
BB035364 |
Product Name: |
Amino-PEG2-t-butyl ester |
CAS: |
756525-95-8 |
Synonyms: |
Amino-PEG2-COOtBu; H2N-PEG2-CH2CH2COOtBu; tert-Butyl 3-(2-(2-aminoethoxy)ethoxy)propanoate |
Related CAS: | 872340-65-3
|
IUPAC Name: | tert-butyl 3-[2-(2-aminoethoxy)ethoxy]propanoate |
Description: | NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 233.30 |
Molecular Formula: | C11H23NO4 |
Canonical SMILES: | CC(C)(C)OC(=O)CCOCCOCCN |
InChI: | InChI=1S/C11H23NO4/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h4-9,12H2,1-3H3 |
InChI Key: | XIVHGTLMLORWEP-UHFFFAOYSA-N |
Boiling Point: | 313.7±22.0 °C at 760 mmHg |
Flash Point: | 103.3±18.7 °C |
Purity: | > 98.0 % |
Density: | 1.0±0.1 g/cm3 |
Solubility: | 10 mm in DMSO |
Appearance: | Colorless to light yellow clear liquid |
Storage: | Store at -5 °C, keep in dry and avoid sunlight. |
LogP: | 0.48 |
Vapor Pressure: | 0.0±0.7 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021207291-A1 | Compounds and uses thereof | 20200406 |
WO-2021155321-A2 | Compounds and uses thereof | 20200129 |
WO-2021003050-A2 | Cd38-binding agents and uses thereof | 20190703 |
CN-112094266-A | Pyrrolopyridinone compound, preparation method, composition and application thereof | 20190617 |
US-2020390899-A1 | Aminobenzazepine compounds, immunoconjugates, and uses thereof | 20190613 |
Complexity: | 189 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 233.16270821 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 233.16270821 |
Rotatable Bond Count: | 10 |
Topological Polar Surface Area: | 70.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.2 |
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