Adenosine 3',5'-Cyclic Monophosphate - CAS 60-92-4
Catalog: |
BB030862 |
Product Name: |
Adenosine 3',5'-Cyclic Monophosphate |
CAS: |
60-92-4 |
Synonyms: |
Cyclic AMP; cAMP; Adenosine 3',5'-cyclophosphate; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-; cyclic Adenosine 3',5'-monophosphate |
Related CAS: | 37839-81-9 (monohydrochloride salt)
|
IUPAC Name: | (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol |
Description: | Adenosine 3',5'-Cyclic Monophosphate is an adenosine derivative with anticancer activity. |
Molecular Weight: | 329.21 |
Molecular Formula: | C10H12N5O6P |
Canonical SMILES: | C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)O |
InChI: | InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1 |
InChI Key: | IVOMOUWHDPKRLL-KQYNXXCUSA-N |
Boiling Point: | 701.5±70.0°C at 760 mmHg |
Melting Point: | 260°C (dec.) |
Purity: | ≥95% |
Density: | 2.47±0.1 g/cm3 (Predicted) |
Solubility: | Soluble in Water |
Appearance: | White Lyophilized Powder |
Storage: | Store at -20°C |
MDL: | MFCD00005845 |
LogP: | -0.23620 |
GHS Hazard Statement: | H314 (25%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P261, P264, P271, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113462764-A | Hairpin-like adaptors, constructs and methods for characterizing double-stranded target polynucleotides | 20210901 |
CN-113480522-A | Novel phenylpyrazole derivative and application thereof in hypoglycemic drugs | 20210819 |
CN-113425734-A | Application of lobetyolin in preparation of medicine for treating diabetes | 20210809 |
CN-113476452-A | Application of thiadiazolo pyrimidine amide compound in preparation of medicines for treating PDE2 disorder diseases | 20210806 |
CN-113499342-A | Application of pyrimidoindole diketone compound in preparing medicament for treating PDE5 disorder disease | 20210806 |
PMID | Publication Date | Title | Journal |
33581290 | 20210515 | Low dose of fire retardant, 2,2',4,4'-tetrabromodiphenyl ether (BDE47), stimulates the proliferation and differentiation of progenitor Leydig cells of male rats during prepuberty | Toxicology letters |
33582287 | 20210515 | Exposure to 4-bromodiphenyl ether during pregnancy blocks testis development in male rat fetuses | Toxicology letters |
33638691 | 20210501 | In vitro effects of the endocrine disruptor p,p'DDT on human choriogonadotropin/luteinizing hormone receptor signalling | Archives of toxicology |
33713149 | 20210501 | A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca2+-signalling | Archives of toxicology |
33757793 | 20210501 | Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO-1, NQO1 signaling | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
Complexity: | 498 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 4 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 329.05252012 |
Formal Charge: | 0 |
Heavy Atom Count: | 22 |
Hydrogen Bond Acceptor Count: | 10 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 329.05252012 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 155 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -2.6 |
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