Acetamide - CAS 60-35-5

Catalog:	BB030663
Product Name:	Acetamide
CAS:	60-35-5
Synonyms:	Ethanamide; Acetic Acid Amide; Methanecarboxamide; Acetimidic Acid; Amide C2

Technical Data

IUPAC Name:	acetamide
Description:	Acetamide is the simplest amide derived from acetic acid. It finds some use as a plasticizer and as an industrial solvent. Acetamide (2.88 g/kg/d) can reduce central nervous lesions, but the efficacy is not improved after increasing the dose.
Molecular Weight:	59.07
Molecular Formula:	C2H5NO
Canonical SMILES:	CC(=O)N
InChI:	InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
InChI Key:	DLFVBJFMPXGRIB-UHFFFAOYSA-N
Boiling Point:	221 °C
Melting Point:	78-81 °C
Purity:	> 98 %
Density:	1.159 g/cm³
Solubility:	Soluble in Water
Appearance:	White crystalline solid
Storage:	Store at 2-8 °C
Decomposition:	Hazardous decomposition products formed under fire conditions - carbon oxides, Nitrogen oxides (nox)
MDL:	MFCD00008023
LogP:	-1.26
Quality Standard:	Enterprise Standard
Refractive Index:	1.4274 at 78 °C/D
Stability:	Stable under recommended storage conditions
Vapor Pressure:	1 mmHg at 149 °F

GHS Hazard Statement:	H351: Suspected of causing cancer [Warning Carcinogenicity]
Precautionary Statement:	P201, P202, P281, P308+P313, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-108845126-A	A kind of chromatography and enzyme chemical method joint-detection gynecology colpitis kit	20180627
CN-108845126-B	A kind of chromatography and enzyme chemical method joint-detection gynecology colpitis kit	20180627
CN-108484467-A	A kind of preparation method of Oseltamivir acetylethyleneimine intermediate	20180409
AU-2018349244-A1	N-acetylneuraminic acid compositions and methods of use	20171011
WO-2019073298-A1	NEURAMINIC ACID COMPOSITIONS AND METHODS OF USE	20171011

PMID	Publication Date	Title	Journal
31881176	20200201	A toxicogenomic approach for the risk assessment of the food contaminant acetamide	Toxicology and applied pharmacology
31735575	20200101	Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors	European journal of medicinal chemistry
30606670	20190201	Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs	Bioorganic & medicinal chemistry
28554091	20170908	Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation	European journal of medicinal chemistry
28108177	20170301	Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models	Toxicology and applied pharmacology

Complexity:	33
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	59.037113783
Formal Charge:	0
Heavy Atom Count:	4
Hydrogen Bond Acceptor Count:	1
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	59.037113783
Rotatable Bond Count:	0
Topological Polar Surface Area:	43.1 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-0.9