8-Oxa-2-azaspiro[4.5]decane - CAS 310-93-0
Catalog: |
BB058411 |
Product Name: |
8-Oxa-2-azaspiro[4.5]decane |
CAS: |
310-93-0 |
Synonyms: |
8-oxa-2-azaspiro[4.5]decane; 8-Oxa-2-aza-spiro[4.5]decane |
IUPAC Name: | 8-oxa-2-azaspiro[4.5]decane |
Description: | 8-Oxa-2-azaspiro[4.5]decane is a useful research chemical compound used in the preparation of hexafluoroisopropyl carbamate-based monoacylglycerol lipase inhibitors as analgesics. |
Molecular Weight: | 179.6 |
Molecular Formula: | C8H15NO |
Canonical SMILES: | C1CNCC12CCOCC2 |
InChI: | InChI=1S/C8H15NO/c1-4-9-7-8(1)2-5-10-6-3-8/h9H,1-7H2 |
InChI Key: | JVBOTGLQUHBBCV-UHFFFAOYSA-N |
References: | Cisar, J. S., et al. J. Med. Chem. 61, 20, 9062-84, (2018). |
GHS Hazard Statement: | H227 (100%): Combustible liquid [Warning Flammable liquids] |
Precautionary Statement: | P210, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P332+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2022002142-A1 | Tetrahydroisoquinoline compounds and use thereof | 20200630 |
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WO-2021046407-A1 | Rip1 inhibitory compounds and methods for making and using the same | 20190906 |
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Complexity: | 118 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 141.115364102 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 141.115364102 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 21.3Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.4 |
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