7- Oxa- 2- azaspiro[3.5] nonane Hydrochloride - CAS 1417633-09-0
Catalog: |
BB056729 |
Product Name: |
7- Oxa- 2- azaspiro[3.5] nonane Hydrochloride |
CAS: |
1417633-09-0 |
Synonyms: |
7-Oxa-2-azaspiro[3.5]nonane hydrochloride; 7-oxa-2-azaspiro[3.5]nonane; hydrochloride; 7-oxa-2-azaspiro[3.5]nonane HCl; 7-Oxa-2-azaspiro[3.5]nonanehydrochloride |
IUPAC Name: | 7-oxa-2-azaspiro[3.5]nonanehydrochloride |
Description: | 7- Oxa- 2- azaspiro[3.5] nonane Hydrochloride is a reagent in the synthesis of MPS1 kinase inhibitors which may be used in anti-cancer treatments. |
Molecular Weight: | 127.18 + (36.46) |
Molecular Formula: | C7H13NO·(HCl) |
Canonical SMILES: | C1COCCC12CNC2.Cl |
InChI: | InChI=1S/C7H13NO.ClH/c1-3-9-4-2-7(1)5-8-6-7/h8H,1-6H21H |
InChI Key: | HJDIPGYOFUZLRF-UHFFFAOYSA-N |
References: | Woodward, H. et al. J. Med. Chem., 61, 8226 (2018). |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021222858-A1 | Antagonists of gpr39 protein | 20200430 |
CN-113493453-A | Fused aromatic ring derivative, preparation method and medical application thereof | 20200407 |
WO-2021173917-A1 | Inhibitors of receptor interacting protein kinase i for the treatment of disease | 20200228 |
WO-2021041671-A1 | Kras g12d inhibitors | 20190829 |
CN-112279848-A | Pan-JAKs inhibitor and application thereof | 20190725 |
WO-2021008455-A1 | Ret selective inhibitor, preparation method therefor and use thereof | 20190712 |
CN-112209925-A | RET selective inhibitor and preparation method and application thereof | 20190712 |
CN-114072404-A | RET selective inhibitor and preparation method and application thereof | 20190712 |
KR-20220018584-A | RET selective inhibitors and methods for their preparation and use | 20190712 |
WO-2020244539-A1 | Pyridone derivative, preparation method therefor, and pharmaceutical application thereof | 20190604 |
Complexity: | 102 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 163.0763918 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 163.0763918 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 21.3Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS