Inquiry Basket
| IUPAC Name: | 7-methoxy-6-(3-morpholin-4-ylpropoxy)-3H-quinazolin-4-one |
| Description: | 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is an intermediate of Gefitinib. Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition. |
| Molecular Weight: | 319.36 |
| Molecular Formula: | C16H21N3O4 |
| Canonical SMILES: | COC1=C(C=C2C(=C1)N=CNC2=O)OCCCN3CCOCC3 |
| InChI: | InChI=1S/C16H21N3O4/c1-21-14-10-13-12(16(20)18-11-17-13)9-15(14)23-6-2-3-19-4-7-22-8-5-19/h9-11H,2-8H2,1H3,(H,17,18,20) |
| InChI Key: | WFUBWLXSYCFZEH-UHFFFAOYSA-N |
| Boiling Point: | 519.5±60.0 °C at 760 mmHg |
| Melting Point: | >243°C (dec.) |
| Density: | 1.32±0.1 g/cm3 |
| Solubility: | Soluble in DMSO (Slightly), Methanol (Slightly) |
| Appearance: | White to Off-white Solid |
| Storage: | Store at 2-8°C |
| LogP: | 0.97070 |
Catalog: BB022405
(S)-3-Methylmorpholine
Detail
Catalog: BB018658
N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate
Detail
Catalog: BB015499
4-(6-Bromohexyl)morpholine Hydrobromide
Detail
Catalog: BB002238
N-Ethyl-2-morpholin-4-ylethanamine
Detail
Catalog: BB029768
4-(3-Chloropropyl)morpholine hydrochloride
Detail
Catalog: BB018496
2-(2,6-Dimethylmorpholin-4-yl)ethanamine
Detail
Catalog: BB003037
(2S,3R)-N-Boc-6-oxo-2,3-diphenylmorpholine
Detail
Catalog: BB022035
Morpholine-2,2,3,3,5,5,6,6-D8
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Morpholines/Thiomorpholines
2,2-Difluoro-N-(2-morpholin-4-ylethyl)ethanamine dihydrochloride
Ethyl 1-methyl-3-(morpholin-4-ylcarbonyl)pyrazole-5-carboxylate
Customers Also Viewed
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
