7-Hydroxy-4-chromone - CAS 59887-89-7
Catalog: |
BB030549 |
Product Name: |
7-Hydroxy-4-chromone |
CAS: |
59887-89-7 |
Synonyms: |
7-hydroxy-4H-chromen-4-one; 7-Hydroxychromone; 7-Hydroxy-4-benzopyrone |
IUPAC Name: | 7-hydroxychromen-4-one |
Description: | 7-Hydroxy-4-chromone is a 4-oxo-4H-1-benzopyran derivative which can inhibit Src kinase with an IC50 of <300 μM. |
Molecular Weight: | 162.14 |
Molecular Formula: | C9H6O3 |
Canonical SMILES: | C1=CC2=C(C=C1O)OC=CC2=O |
InChI: | InChI=1S/C9H6O3/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5,10H |
InChI Key: | WVJCRTSTRGRJJT-UHFFFAOYSA-N |
Boiling Point: | 345.4 °C at 760 mmHg |
Density: | 1.403 g/cm3 |
MDL: | MFCD00209371 |
LogP: | 1.49860 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P312, P330, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113174376-A | Application of polyphenol oxidase and method for synthesizing flavone | 20210425 |
CN-113149941-A | Ether compound and pharmaceutical application thereof in preventing and treating diabetes and metabolic syndrome | 20200122 |
EP-3854455-A1 | Ttp phosphorylation as a biomarker in targeted therapy | 20191211 |
US-2021177852-A1 | Ttp phosphorylation as a biomarker in targeted therapy | 20191211 |
CN-110386910-A | A kind of preparation method of furans and chromene compound C33 process impurity | 20190415 |
PMID | Publication Date | Title | Journal |
21210738 | 20110501 | C5-hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2 | Xenobiotica; the fate of foreign compounds in biological systems |
20665371 | 20110101 | Novel flavonoids from the leaves of Actinidia valvata Dunn: structural elucidation and antioxidant activity | Planta medica |
21461045 | 20100101 | Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease | PPAR research |
19807106 | 20091112 | 7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists | Journal of medicinal chemistry |
18267976 | 20080501 | Isoflavones promote mitochondrial biogenesis | The Journal of pharmacology and experimental therapeutics |
Complexity: | 222 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 162.031694049 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 162.031694049 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 46.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.4 |
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