7-Fluoro-4-hydroxyquinazoline - CAS 1210824-60-4
Catalog: |
BB005030 |
Product Name: |
7-Fluoro-4-hydroxyquinazoline |
CAS: |
1210824-60-4 |
Synonyms: |
7-fluoro-3H-quinazolin-4-one; 7-fluoro-3H-quinazolin-4-one |
IUPAC Name: | 7-fluoro-3H-quinazolin-4-one |
Description: | 7-Fluoro-4-hydroxyquinazoline (CAS# 1210824-60-4 ) is a useful research chemical. |
Molecular Weight: | 164.14 |
Molecular Formula: | C8H5FN2O |
Canonical SMILES: | C1=CC2=C(C=C1F)N=CNC2=O |
InChI: | InChI=1S/C8H5FN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12) |
InChI Key: | KCORZHJVTZIZFD-UHFFFAOYSA-N |
GHS Hazard Statement: | H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112300132-A | Aryl quinazoline DNA-PK inhibitor | 20190730 |
WO-2020210481-A1 | Heterocyclic compounds as kinase inhibitors for therapeutic uses | 20190412 |
TW-202104212-A | Heterocyclic compounds as kinase inhibitors for therapeutic uses | 20190412 |
CN-109206377-B | Novel method for preparing N- (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro-4-quinazolinamine | 20180919 |
TW-202003734-A | Resin composition, laminate, semiconductor wafer with resin composition layer, mounting substrate for semiconductor with resin composition layer, and semiconductor device | 20180426 |
PMID | Publication Date | Title | Journal |
22365563 | 20120401 | Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors | European journal of medicinal chemistry |
Complexity: | 229 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 164.03859095 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 164.03859095 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 41.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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