7-Ethyltryptophol - CAS 41340-36-7
Catalog: |
BB056066 |
Product Name: |
7-Ethyltryptophol |
CAS: |
41340-36-7 |
Synonyms: |
7-Ethyl-indole-3-ethanol; 2-(7-Ethyl-1H-indol-3-yl)-ethanol; 3-(2-Hydroxyethyl)-7-ethylindole; 7-Ethyl-1H-indole-3-ethanol; 7-Ethyl-3-indoleethanol; Etodolac Impurity H; Etodolac EP Impurity H |
IUPAC Name: | 2-(7-ethyl-1H-indol-3-yl)ethanol |
Description: | 7-Ethyltryptophol (Etodolac EP Impurity H) is a key intermediate in the preparation of the non-steroidal anti-inflammatory drug Etodolac. |
Molecular Weight: | 189.25 |
Molecular Formula: | C12H15NO |
Canonical SMILES: | CCC1=C2C(=CC=C1)C(=CN2)CCO |
InChI: | InChI=1S/C12H15NO/c1-2-9-4-3-5-11-10(6-7-14)8-13-12(9)11/h3-5,8,13-14H,2,6-7H2,1H3 |
InChI Key: | UVSDNCAZVSQJQA-UHFFFAOYSA-N |
Melting Point: | 44-45°C |
Solubility: | Chloroform (Slightly), Methanol (Slightly) |
Appearance: | White to Pale Beige Solid |
Storage: | 4°C |
References: | El Kousy, N., et al. J. Pharm. Biomed. Anal., 20, 185 (1999),. |
GHS Hazard Statement: | H302: Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P264, P270, P273, P301+P317, P319, P330, P391, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113929612-A | Preparation method of etodolac intermediate | 20200629 |
CN-113666860-A | Preparation method of 7-ethyl tryptophol | 20200514 |
CN-111303172-A | Method for preparing etodolac methyl ester | 20200318 |
CN-111303172-B | Method for preparing etodolac methyl ester | 20200318 |
US-11046705-B1 | Method for preparing etodolac methyl ester | 20200318 |
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CN-208320023-U | A kind of rectifying device applied to 7- ethyl tryptophol | 20180228 |
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PMID | Publication Date | Title | Journal |
19177910 | 20081201 | Improvement of the etodolac purity test by reversed phase high-performance liquid chromatography | Die Pharmazie |
Complexity: | 183 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 189.115364102 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 189.115364102 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 36Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.4 |
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