7-Azaindole - CAS 271-63-6
Catalog: |
BB019487 |
Product Name: |
7-Azaindole |
CAS: |
271-63-6 |
Synonyms: |
1H-pyrrolo[2,3-b]pyridine |
IUPAC Name: | 1H-pyrrolo[2,3-b]pyridine |
Description: | Imidazolinone derivatives as CGRP receptor antagonists used in the treatment of migraine. |
Molecular Weight: | 118.14 |
Molecular Formula: | C7H6N2 |
Canonical SMILES: | C1=CC2=C(NC=C2)N=C1 |
InChI: | InChI=1S/C7H6N2/c1-2-6-3-5-9-7(6)8-4-1/h1-5H,(H,8,9) |
InChI Key: | MVXVYAKCVDQRLW-UHFFFAOYSA-N |
Boiling Point: | 270 °C |
Purity: | 97% |
MDL: | MFCD00005606 |
LogP: | 1.56290 |
GHS Hazard Statement: | H302 (73.33%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (73.33%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (26.67%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (93.33%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
US-10988479-B1 | Morphic forms of trilaciclib and methods of manufacture thereof | 20200615 |
EP-3858438-A1 | 3,4-dihydro-2h-spiro[isoquinoline-1,4'-piperidin]amide derivatives having multimodal activity against pain | 20200203 |
EP-3858439-A1 | Amide derivatives having multimodal activity against pain | 20200203 |
EP-3858810-A1 | Dialkylaminoarylcycloalkylamide derivatives having multimodal activity against pain | 20200203 |
WO-2021144287-A1 | 3-benzoyl-1h-pyrrolo[2,3-b]pyridine derivatives as mkk4 inhibitors for treating liver diseases | 20200115 |
PMID | Publication Date | Title | Journal |
32787140 | 20200910 | Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials | Journal of medicinal chemistry |
31136173 | 20190627 | Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity | Journal of medicinal chemistry |
24225656 | 20140114 | The acid-catalysed synthesis of 7-azaindoles from 3-alkynyl-2-aminopyridines and their antimicrobial activity | Organic & biomolecular chemistry |
23051946 | 20121128 | Synthesis of functionalized 2-aryl-4-(indol-3-yl)-4H-chromenes via iodine-catalyzed domino Michael addition-intramolecular cyclization reaction | Organic & biomolecular chemistry |
22925984 | 20121101 | Spectroscopic study of the ground and excited state prototropic equilibria of 4-azaindole | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy |
Complexity: | 103 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 118.0530982 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 118.0530982 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 28.7 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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