7-aminothieno[2,3-b]pyrazine-6-carboxylic acid - CAS 56881-31-3
Catalog: |
BB029520 |
Product Name: |
7-aminothieno[2,3-b]pyrazine-6-carboxylic acid |
CAS: |
56881-31-3 |
Synonyms: |
7-amino-6-thieno[2,3-b]pyrazinecarboxylic acid; 7-aminothieno[2,3-b]pyrazine-6-carboxylic acid |
IUPAC Name: | 7-aminothieno[2,3-b]pyrazine-6-carboxylic acid |
Description: | 7-aminothieno[2,3-b]pyrazine-6-carboxylic acid (CAS# 56881-31-3) is used as a reactant in the preparation of thieno[2,3-b]pyrazine derivatives as B-Raf inhibitors. |
Molecular Weight: | 195.20 |
Molecular Formula: | C7H5N3O2S |
Canonical SMILES: | C1=CN=C2C(=N1)C(=C(S2)C(=O)O)N |
InChI: | InChI=1S/C7H5N3O2S/c8-3-4-6(10-2-1-9-4)13-5(3)7(11)12/h1-2H,8H2,(H,11,12) |
InChI Key: | UJUCBOIXAMPUQL-UHFFFAOYSA-N |
Boiling Point: | 465 °C at 760 mmHg |
Density: | 1.707 g/cm3 |
LogP: | 1.55290 |
Publication Number | Title | Priority Date |
US-10040802-B2 | Thienopyrazine inhibitors of IRAK4 activity | 20150312 |
US-2018051035-A1 | Thienopyrazine inhibitors of irak4 activity | 20150312 |
EP-3268003-B1 | Thienopyrazine inhibitors of irak4 activity | 20150312 |
EP-2576566-A1 | Thieno (2, 3b) pyrazine compounds as b - raf inhibitors | 20100528 |
EP-2576566-B1 | Thieno(2,3b)pyrazine compounds as b-raf inhibitors | 20100528 |
Complexity: | 226 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 195.01024758 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 195.01024758 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 117 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1 |
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