6-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic Acid - CAS 1018828-69-7
Catalog: |
BB000684 |
Product Name: |
6-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic Acid |
CAS: |
1018828-69-7 |
Synonyms: |
6-(trifluoromethyl)-2-imidazo[1,2-a]pyridinecarboxylic acid; 6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid |
IUPAC Name: | 6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid |
Description: | 6-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic Acid (CAS# 1018828-69-7) is a useful research chemical. |
Molecular Weight: | 230.14 |
Molecular Formula: | C9H5F3N2O2 |
Canonical SMILES: | C1=CC2=NC(=CN2C=C1C(F)(F)F)C(=O)O |
InChI: | InChI=1S/C9H5F3N2O2/c10-9(11,12)5-1-2-7-13-6(8(15)16)4-14(7)3-5/h1-4H,(H,15,16) |
InChI Key: | KASXDWUVBQTSFN-UHFFFAOYSA-N |
Storage: | Sealed in dry, 2-8 °C |
MDL: | MFCD09258865 |
LogP: | 2.05130 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021126728-A1 | Prmt5 inhibitors | 20191217 |
WO-2019102494-A1 | Heterocyclic compounds as prmt5 inhibitors | 20171124 |
BR-112020010322-A2 | compound of the formula i; compound of the formula ia; compound of the formula ib; process for preparing compounds of formula i; pharmaceutical composition; method for the treatment and / or prevention of various diseases; use of compounds; method for treating cancer; and method for the treatment and / or prevention of a prmt5-mediated condition or a proliferative disorder or cancer | 20171124 |
EP-3704120-A1 | Heterocyclic compounds as prmt5 inhibitors | 20171124 |
IL-274762-D0 | New heterocyclic compounds as prmt5 inhibitors | 20171124 |
Complexity: | 295 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 230.03031189 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 230.03031189 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 54.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.5 |
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