6-Methyl-8-quinoxalinesulfonyl Chloride - CAS 21863-51-4
Catalog: |
BB059497 |
Product Name: |
6-Methyl-8-quinoxalinesulfonyl Chloride |
CAS: |
21863-51-4 |
Synonyms: |
6-methylquinoline-8-sulfonyl chloride; 6-Methyl-8-quinoxalinesulfonyl Chloride; 6-methyl-8-quinolinesulfonyl chloride; 6-Methylquinoline-8-sulfonylchloride; 6-methyl-quinoline-8-sulfonyl chloride |
IUPAC Name: | 6-methylquinoline-8-sulfonyl chloride |
Description: | 6-Methyl-8-quinoxalinesulfonyl Chloride similar to other quinoxalinesulfonyl compounds can be used in the preparation of 8-mercaptoquinoline derivatives as well as various sulfonamides. In addition, the compound itself has the potential to inhibit tyrosine kinases. |
Molecular Weight: | 241.69 |
Molecular Formula: | C10H8ClNO2S |
Canonical SMILES: | CC1=CC2=C(C(=C1)S(=O)(=O)Cl)N=CC=C2 |
InChI: | InChI=1S/C10H8ClNO2S/c1-7-5-8-3-2-4-12-10(8)9(6-7)15(11,13)14/h2-6H,1H3 |
InChI Key: | JZXUJBAZGSPYJP-UHFFFAOYSA-N |
References: | Ragheb, A. et al. J. Serb. Chem., 52, 697 (1987); Lai, J. et al. Synthet. Comm., 33, 3427 (2003); Yvonne, F. et al. Medicin. Res. Rev., 25, 310 (2005). |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
AU-2005279795-A1 | Bicyclic heteroaryl PDE4B inhibitors | 20040903 |
CA-2583428-A1 | Bicyclic heteroaryl pde4b inhibitors | 20040903 |
EP-1786813-A2 | Bicyclic heteroaryl pde4b inhibitors | 20040903 |
JP-2008512380-A | PDE4B inhibitor | 20040903 |
US-2006100218-A1 | PDE4B inhibitors | 20040903 |
US-7605168-B2 | PDE4B inhibitors | 20040903 |
WO-2006026754-A2 | Bicyclic heteroaryl pde4b inhibitors | 20040903 |
WO-2006026754-A9 | Bicyclic heteroaryl pde4b inhibitors | 20040903 |
CZ-63994-A3 | The heterocyclic sulfonamide derivative and the pharmaceutical composition containing it | 19940318 |
NZ-260127-A | Sulphonamido azacycloalkyl derivatives and medicaments | 19940317 |
Complexity: | 325 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 240.9964274 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 240.9964274 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 55.4Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.6 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS