6-Hydroxyisoquinoline - CAS 7651-82-3
Catalog: |
BB035596 |
Product Name: |
6-Hydroxyisoquinoline |
CAS: |
7651-82-3 |
Synonyms: |
6-isoquinolinol; isoquinolin-6-ol |
IUPAC Name: | isoquinolin-6-ol |
Description: | 6-Hydroxyisoquinoline (CAS# 7651-82-3) is used in proteomics research such as in preparation of isoquinoline derivatives which act as protease inhibitors against trypsin. It was also used as a reagent in the study of a novel series of compounds that act as Wnt signaling pathway inhibitors and obtained by scaffold hybridization strategy from two known porcupine inhibitor classes. |
Molecular Weight: | 145.16 |
Molecular Formula: | C9H7NO |
Canonical SMILES: | C1=CC2=C(C=CN=C2)C=C1O |
InChI: | InChI=1S/C9H7NO/c11-9-2-1-8-6-10-4-3-7(8)5-9/h1-6,11H |
InChI Key: | GPVPDRHTRGTSIH-UHFFFAOYSA-N |
Boiling Point: | 332.1 °C at 760 mmHg |
Density: | 1.26 g/cm3 |
MDL: | MFCD04114860 |
LogP: | 1.94040 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2021147386-A1 | Pyrrolidine and piperidine compounds | 20191106 |
WO-2021090245-A1 | Pyrrolidine and piperidine compounds | 20191106 |
CN-110437062-A | It is a kind of how the synthetic method of his your intermediate of ground | 20190823 |
WO-2021009206-A1 | Compound and an organic semiconducting layer, an organic electronic device, a display device and a lighting device comprising the same | 20190715 |
EP-3747883-A1 | Monocyclic b-lactam compound for treating bacterial infection | 20180129 |
PMID | Publication Date | Title | Journal |
11911193 | 20020301 | Structure activity relationships of new inhibitors of mammalian 2,3-oxidosqualene cyclase designed from isoquinoline derivatives | Chemical & pharmaceutical bulletin |
Complexity: | 138 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 145.052763847 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 145.052763847 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 33.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.9 |
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Quinoline/Isoquinoline
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