![6'-Cyano-2',3'-dihydro-α-methyl-5'-oxospiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic Acid Ethyl Ester](https://resource.bocsci.com/structure/1586782-19-5.gif)
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| IUPAC Name: | ethyl 2-(6'-cyano-5'-oxospiro[1,3-dioxolane-2,1'-2,3-dihydroindolizine]-7'-yl)propanoate |
| Description: | 6'-Cyano-2',3'-dihydro-α-methyl-5'-oxospiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic Acid Ethyl Ester is a key intermediate in the synthesis of camptothecin (C175150) analogues. |
| Molecular Weight: | 318.32 |
| Molecular Formula: | C16H18N2O5 |
| Canonical SMILES: | CCOC(=O)C(C)C1=C(C(=O)N2CCC3(C2=C1)OCCO3)C#N |
| InChI: | InChI=1S/C16H18N2O5/c1-3-21-15(20)10(2)11-8-13-16(22-6-7-23-16)4-5-18(13)14(19)12(11)9-17/h8,10H,3-7H2,1-2H3 |
| InChI Key: | ZXDNGJPDHJGXHD-UHFFFAOYSA-N |
| Solubility: | DCM, Chloroform |
| Appearance: | White Solid |
| References: | Fan, Y., et al. J. Med. Chem., 41, 2216 (1998), Kaufmann, S.H., et al. Biochim. Biophys. Acta, 1400, 195 (1998),. |
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