6-Bromopyridine-3-boronic Acid Pinacol Ester - CAS 214360-62-0
Catalog: |
BB016859 |
Product Name: |
6-Bromopyridine-3-boronic Acid Pinacol Ester |
CAS: |
214360-62-0 |
Synonyms: |
2-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine |
IUPAC Name: | 2-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine |
Description: | 6-Bromopyridine-3-boronic Acid Pinacol Ester (CAS# 214360-62-0) is a useful research chemical. |
Molecular Weight: | 283.96 |
Molecular Formula: | C11H15BrNO2B |
Canonical SMILES: | B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)Br |
InChI: | InChI=1S/C11H15BBrNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-9(13)14-7-8/h5-7H,1-4H3 |
InChI Key: | MEGBELYYUPCOIQ-UHFFFAOYSA-N |
Boiling Point: | 119-120 °C / 19 mmHg |
Density: | 1.04 g/cm3 |
MDL: | MFCD03412794 |
LogP: | 2.14330 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
Precautionary Statement: | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020228756-A1 | Inhibitor containing bicyclic derivative, preparation method therefor and use thereof | 20190514 |
CN-112368283-A | Bicyclic derivative-containing inhibitor, preparation method and application thereof | 20190514 |
US-2020339530-A1 | Urea derivatives as inhibitors of ask1 | 20171117 |
KR-20100129774-A | Polysubstituted derivatives of 2-aryl-6-phenyl-imidazo [1,2-a] pyridine, and their preparation and therapeutic uses | 20080321 |
US-2011046372-A1 | Novel boron compounds, their production processes, and functional electronic devices using same | 20071206 |
PMID | Publication Date | Title | Journal |
14532682 | 20031001 | 2-bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, a new unexpected bifunctional building block for combinatorial chemistry | Acta crystallographica. Section C, Crystal structure communications |
12711779 | 20030301 | 2-(6-bromopyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane and (6-bromopyridin-3-yl)boronic acid, new bifunctional building blocks for combinatorial chemistry | Acta crystallographica. Section C, Crystal structure communications |
Complexity: | 257 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 283.03792 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 283.03792 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 31.4 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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