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| IUPAC Name: | 5-bromo-2-oxo-1H-pyrazine-3-carboxylic acid |
| Description: | 6-Bromo-3-hydroxypyrazine-2-carboxylic Acid is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. |
| Molecular Weight: | 217.93 |
| Molecular Formula: | C5H3BrN2O3 |
| Canonical SMILES: | C1=C(N=C(C(=O)N1)C(=O)O)Br |
| InChI: | InChI=1S/C5H3BrN2O3/c6-2-1-7-4(9)3(8-2)5(10)11/h1H,(H,7,9)(H,10,11) |
| InChI Key: | VMCUQNUHUVHRIL-UHFFFAOYSA-N |
| References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014). |
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