6-Bromo-3-hydroxypicolinamide - CAS 188923-77-5
Catalog: |
BB071088 |
Product Name: |
6-Bromo-3-hydroxypicolinamide |
CAS: |
188923-77-5 |
Synonyms: |
6-Bromo-3-hydroxypyridine-2-carboxamide |
IUPAC Name: | 6-bromo-3-hydroxypyridine-2-carboxamide |
Description: | 6-Bromo-3-hydroxypicolinamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. |
Molecular Weight: | 217.02 |
Molecular Formula: | C6H5BrN2O2 |
Canonical SMILES: | C1=CC(=NC(=C1O)C(=O)N)Br |
InChI: | InChI=1S/C6H5BrN2O2/c7-4-2-1-3(10)5(9-4)6(8)11/h1-2,10H,(H2,8,11) |
InChI Key: | OLMQCQCXXHPXCG-UHFFFAOYSA-N |
References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014). |
Complexity: | 165 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 215.95344 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 215.95344 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 76.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.3 |
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