6-Azauracil - CAS 461-89-2
Catalog: |
BB026093 |
Product Name: |
6-Azauracil |
CAS: |
461-89-2 |
Synonyms: |
2H-1,2,4-triazine-3,5-dione |
Application: |
Inhibits enzymes in nucleoside synthesis and depletes the intracellular GTP/UTP pool |
IUPAC Name: | 2H-1,2,4-triazine-3,5-dione |
Description: | 6-Azauracil inhibits enzymes in nucleoside synthesis and depletes the intracellular GTP/UTP pool. It is being used to identify mutations in transcriptional elongation machinery, as well as mutations in a variety of other pathways. |
Molecular Weight: | 113.07 |
Molecular Formula: | C3H3N3O2 |
Canonical SMILES: | C1=NNC(=O)NC1=O |
InChI: | InChI=1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8) |
InChI Key: | SSPYSWLZOPCOLO-UHFFFAOYSA-N |
Boiling Point: | 503.4 °C at 760 mmHg |
Melting Point: | 276-280 °C |
Purity: | ≥ 98 % |
Density: | 1.86 g/cm3 |
Solubility: | Soluble in DMSO |
Appearance: | White solid. |
Storage: | Store at -20 °C |
MDL: | MFCD00006456 |
LogP: | -1.54180 |
Quality Standard: | Enterprise standard |
Publication Number | Title | Priority Date |
CN-112479753-A | Water-soluble fertilizer synergist and preparation method thereof | 20201215 |
CN-112592402-A | anti-DKK 2 antibodies, compositions comprising the anti-DKK 2 antibodies, and uses thereof | 20201202 |
CN-112457363-A | Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof | 20201123 |
CN-111759851-A | Application of tannic acid in preparing anti-coronavirus medicine | 20200817 |
CN-111759851-B | Application of tannic acid in preparing anti-coronavirus medicine | 20200817 |
PMID | Publication Date | Title | Journal |
22547202 | 20120901 | Molecular and functional properties of P2X receptors--recent progress and persisting challenges | Purinergic signalling |
22747063 | 20120802 | Electron configuration and hydrogen-bonding pattern in several thymine and uracil analogues studied by 1H-14N NQDR and DFT/QTAIM | The journal of physical chemistry. B |
22377631 | 20120501 | Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae | Genetics |
22670226 | 20120501 | Identification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae | G3 (Bethesda, Md.) |
22160571 | 20120401 | Inositol phosphate kinase Vip1p interacts with histone chaperone Asf1p in Saccharomyces cerevisiae | Molecular biology reports |
Complexity: | 162 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 113.022526347 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 113.022526347 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 70.6 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.6 |
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