6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one(Anagrelide Impurity) - CAS 875467-41-7

Catalog: BB068042
Product Name: 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one(Anagrelide Impurity)
CAS: 875467-41-7
Synonyms: 6,7-dichloro-1-hydroxy-3,5-dihydro-1H-imidazo[1,2-a]quinazolin-2-one; 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one(Anagrelide Impurity); 1-Hydroxy-6,7-dichloro-1,2,3,5-tetrahydroimidazo[1,2-a]quinazoline-2-one; 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one (Anagrelide Impurity)
6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one(Anagrelide Impurity)
IUPAC Name:6,7-dichloro-1-hydroxy-3,5-dihydro-1H-imidazo[1,2-a]quinazolin-2-one
Description:1-Hydroxy Anagrelide, is an intermediate for the synthesis of 3-Hydroxy Anagrelide, a major metabolite of Anagrelide, an antithrombotic.
Molecular Weight:272.09
Molecular Formula:C10H7Cl2N3O2
Canonical SMILES:C1C2=C(C=CC(=C2Cl)Cl)N3C(C(=O)NC3=N1)O
InChI:InChI=1S/C10H7Cl2N3O2/c11-5-1-2-6-4(7(5)12)3-13-10-14-8(16)9(17)15(6)10/h1-2,9,17H,3H2,(H,13,14,16)
InChI Key:SPQQGKKQCRFNPT-UHFFFAOYSA-N
Melting Point:>169°C (dec.)
Solubility:DMSO (Slightly, Heated and Sonicated)
Appearance:White to Pale Beige Solid
Storage:Hygroscopic, -20°C Freezer, Under inert atmosphere
References:Fleming, J.S., et al. Thromb. Res., 15, 373 (1979), Seiler, S., et al. J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al. N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al. Drugs, 47, 809 (1994),.

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