6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one - CAS 36725-28-7
Catalog: |
BB023046 |
Product Name: |
6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one |
CAS: |
36725-28-7 |
Synonyms: |
3-(4-aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one; 3-(4-aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one |
IUPAC Name: | 3-(4-aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one |
Description: | AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It's an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity. |
Molecular Weight: | 203.24 |
Molecular Formula: | C11H13N3O |
Canonical SMILES: | CC1CC(=O)NN=C1C2=CC=C(C=C2)N |
InChI: | InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15) |
InChI Key: | GDMRFHZLKNYRRO-UHFFFAOYSA-N |
Density: | 1.3 g/cm3 |
LogP: | 1.90870 |
Publication Number | Title | Priority Date |
CN-110885315-A | Preparation method of important intermediate of levosimendan | 20191213 |
WO-2021013693-A1 | Antibody drug conjugates (adcs) with nampt inhibitors | 20190723 |
WO-2020130214-A1 | Novel hydrazone derivative with aryl or heteroaryl group substituted at terminal amine group thereof and use thereof | 20181219 |
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Complexity: | 280 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 203.105862047 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 203.105862047 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 67.5 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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Pyridazines
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