![(5R,6R,7S,8R,8aS)-6,7,8-Trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione](https://resource.bocsci.com/structure/109944-15-2.gif)
Inquiry Basket
| IUPAC Name: | (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)-1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-2,3-dione |
| Description: | (5R,6R,7S,8R,8aS)-6,7,8-Trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione (CAS# 109944-15-2) is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis.When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin. |
| Molecular Weight: | 232.19 |
| Molecular Formula: | C8H12N2O6 |
| Canonical SMILES: | C(C1C(C(C(C2N1C(=O)C(=O)N2)O)O)O)O |
| InChI: | InChI=1S/C8H12N2O6/c11-1-2-3(12)4(13)5(14)6-9-7(15)8(16)10(2)6/h2-6,11-14H,1H2,(H,9,15)/t2-,3-,4+,5+,6+/m1/s1 |
| InChI Key: | OIURYJWYVIAOCW-PQMKYFCFSA-N |
| Melting Point: | >208°C (dec.) |
| Density: | 1.85±0.1 g/cm3 (Predicted) |
| Solubility: | Soluble in DMSO (Slightly, Heated), Methanol (Very Slightly, Heated, Sonicated), Water (Very Slightly) |
| Appearance: | White to Off-white Solid |
| Storage: | Store at -20°C |
| MDL: | MFCD00270017 |
| LogP: | -4.00520 |
Catalog: BB000104
2-(Boc-amino)-5-(hydroxymethyl)thiazole
Detail
Catalog: BB001769
Ethyl (R)-(-)-Mandelate
Detail
Catalog: BB000198
4-(Hydroxymethyl)-5-methylisoxazole
Detail
Catalog: BB001649
1-(4-Bromobenzyl)-3-hydroxyazetidine
Detail
Catalog: BB000402
4-(Hydroxymethyl)benzaldehyde Oxime
Detail
Catalog: BB001159
N-Cbz-1-(hydroxymethyl)cyclopropylamine
Detail
Catalog: BB001442
(R)-3-Hydroxy-1-methylpyrrolidine
Detail
Catalog: BB044026
Carbamoyloxyurea
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Alcohols and Derivatives
Customers Also Viewed
Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
