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| Description: | (5R,11R)-5,11-Diethyl-2,8-dimethoxy-5,6,11,12-tetrahydrochrysene is an intermediate in the synthesis of cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol (D445070), a fluorescent and selective ligand that can be used to investigate the interactions between ligand and receptor of estrogen receptors (ERs) (1,2,3). cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is an ERα agonist and an ERβ antagonist. |
| Molecular Weight: | 348.49 |
| Molecular Formula: | C24H28O2 |
| References: | Sumbayev, V. V., et al. Mol Cell Endocrinol 287, 30 (2008), Dobrydneva, Y., et al. J. Cardiovasc. Pharmacol., 40, 399 (2002), Rosado, J., et al. Biochem. J., 350, 631 (2000).. |
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