5'-O-DMT-2'-O-methyluridine - CAS 103285-22-9

Name: 5'-O-DMT-2'-O-methyluridine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB001073
Product Name:	5'-O-DMT-2'-O-methyluridine
CAS:	103285-22-9
Synonyms:	5'-DMT-2'-(O-Methyl) Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-Methyluridine; 5'-O-DMT-2'-O-methyl-D-uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyluridine

Technical Data

IUPAC Name:	1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Description:	It is used for RNA synthesis and nucleoside modification.
Molecular Weight:	560.59
Molecular Formula:	C31H32N2O8
Canonical SMILES:	COC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O
InChI:	InChI=1S/C31H32N2O8/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)33-18-17-26(34)32-30(33)36/h4-18,25,27-29,35H,19H2,1-3H3,(H,32,34,36)/t25-,27-,28-,29-/m1/s1
InChI Key:	MFDHAVFJDSRPKC-YXINZVNLSA-N
Purity:	≥98% by HPLC
Density:	1.35±0.1 g/cm³(Predicted)
Appearance:	White to light yellow powder
Storage:	Store at 2-8 °C
LogP:	2.83580

Publication Number	Title	Priority Date
CN-113166190-A	Oligonucleotides and prodrugs	20181123
KR-20190015277-A	5'-cyclo-phosphonate modified nucleotides	20160606
US-2019085012-A1	5'-Cyclo-Phosphonate Modified Nucleotides	20160606
US-11078227-B2	5â€²-cyclo-phosphonate modified nucleotides	20160606
EP-3315507-A1	Oligonucleotide derivative	20150626

Complexity:	884
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	4
Defined Bond Stereocenter Count:	0
Exact Mass:	560.21586598
Formal Charge:	0
Heavy Atom Count:	41
Hydrogen Bond Acceptor Count:	8
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	560.21586598
Rotatable Bond Count:	10
Topological Polar Surface Area:	116
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3.2