5-Nitro-2-(propylthio)pyrimidin-4-ol

Catalog:	BB075772
Product Name:	5-Nitro-2-(propylthio)pyrimidin-4-ol

Technical Data

Description:	5-Nitro-2-(propylthio)pyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
Molecular Weight:	215.23
Molecular Formula:	C7H9N3O3S
References:	Matetzky, S., et al. Circulation, 109, 3171 (2004), Bassand, J., et al. Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al. Cardiovasc. Drug Rev., 25, 357 (2007).

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