5-Iodocytidine - CAS 1147-23-5

Name: 5-Iodocytidine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB003422
Product Name:	5-Iodocytidine
CAS:	1147-23-5
Synonyms:	1-β-D-Ribofuranosyl-5-iodocytosine; 5-Iodo-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-Iodo-ribo Cytidine

Technical Data

IUPAC Name:	4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
Description:	5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions.
Molecular Weight:	369.11
Molecular Formula:	C9H12IN3O5
Canonical SMILES:	C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)I
InChI:	InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
InChI Key:	LQQGJDJXUSAEMZ-UAKXSSHOSA-N
Boiling Point:	565.5±60.0 °C at 760 mmHg
Melting Point:	>160 °C (dec.)
Purity:	≥95%
Density:	2.52±0.1 g/cm³ (Predicted)
Solubility:	Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance:	White solid
Storage:	Store at -20 °C
MDL:	MFCD00056070
LogP:	-1.37720

Publication Number	Title	Priority Date
WO-2021207085-A1	Synthetic elaboration of native dna by rass (sendr)	20200406
US-2021290752-A1	Compositions and methods for inducing immune responses	20200309
US-2021290756-A1	Coronavirus vaccine compositions and methods	20200309
WO-2021183563-A1	Coronavirus vaccine compositions and methods	20200309
WO-2021183564-A1	Compositions and methods for inducing immune responses	20200309

PMID	Publication Date	Title	Journal
21982570	20111001	Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging	Nuclear medicine and biology
18066787	20070101	Synthesis of pyrene labeled RNA for fluorescence measurements	Nucleosides, nucleotides & nucleic acids

Complexity:	426
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	4
Defined Bond Stereocenter Count:	0
Exact Mass:	368.98217
Formal Charge:	0
Heavy Atom Count:	18
Hydrogen Bond Acceptor Count:	5
Hydrogen Bond Donor Count:	4
Isotope Atom Count:	0
Monoisotopic Mass:	368.98217
Rotatable Bond Count:	2
Topological Polar Surface Area:	129
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-1.7