5-(Hydroxymethyl)-1H-indazole - CAS 478828-52-3
Catalog: |
BB026418 |
Product Name: |
5-(Hydroxymethyl)-1H-indazole |
CAS: |
478828-52-3 |
Synonyms: |
1H-indazol-5-ylmethanol; 1H-indazol-5-ylmethanol |
IUPAC Name: | 1H-indazol-5-ylmethanol |
Description: | 5-(Hydroxymethyl)-1H-indazole (CAS# 478828-52-3) is an intermediate used in the preparation of novel Curcumin derivatives as β-secretase inhibitors. |
Molecular Weight: | 148.16 |
Molecular Formula: | C8H8N2O |
Canonical SMILES: | C1=CC2=C(C=C1CO)C=NN2 |
InChI: | InChI=1S/C8H8N2O/c11-5-6-1-2-8-7(3-6)4-9-10-8/h1-4,11H,5H2,(H,9,10) |
InChI Key: | UIXLZPHPSJUXBX-UHFFFAOYSA-N |
Boiling Point: | 380.3 °C at 760 mmHg |
Density: | 1.36 g/cm3 |
Appearance: | Yellow solid |
MDL: | MFCD04038636 |
LogP: | 1.05520 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021032148-A1 | Aminopyrazine compounds as hpk1 inhibitor and the use thereof | 20190821 |
WO-2020186220-A1 | Compounds as inhibitors of macrophage migration inhibitory factor | 20190313 |
JP-2020128368-A | Medicine containing an azole-substituted pyridine compound as an active ingredient | 20190208 |
CN-110914254-A | Azole-substituted pyridine compound | 20170810 |
EP-3666766-A1 | Pyridine compound substituted with azole | 20170810 |
Complexity: | 140 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 148.063662883 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 148.063662883 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 48.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.9 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Alcohols and Derivatives
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS