5-Hydroxy-1H-indazole - CAS 15579-15-4
Catalog: |
BB011161 |
Product Name: |
5-Hydroxy-1H-indazole |
CAS: |
15579-15-4 |
Synonyms: |
1H-indazol-5-ol |
IUPAC Name: | 1H-indazol-5-ol |
Description: | 5-Hydroxy-1H-indazole (CAS# 15579-15-4) is a possible Rho kinase inhibitor. It is also used to discover (sulfamoylphenyl)indazolyl acetamides and carboxamides as inhibitors of mitotic kinase TTK. |
Molecular Weight: | 134.14 |
Molecular Formula: | C7H6N2O |
Canonical SMILES: | C1=CC2=C(C=C1O)C=NN2 |
InChI: | InChI=1S/C7H6N2O/c10-6-1-2-7-5(3-6)4-8-9-7/h1-4,10H,(H,8,9) |
InChI Key: | ZHDXWEPRYNHNDC-UHFFFAOYSA-N |
Boiling Point: | 366.5 °C at 760 mmHg |
Purity: | 98 % |
Density: | 1.434 g/cm3 |
MDL: | MFCD01938124 |
LogP: | 1.26850 |
GHS Hazard Statement: | H302 (95.56%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
US-2021301175-A1 | Polishing composition | 20200330 |
US-2021315896-A1 | Indazole based compounds and associated methods of use | 20200321 |
WO-2021121420-A1 | Benzopyrazole compound and intermediate, preparation method, and application thereof | 20191220 |
WO-2021127397-A1 | Nitrogen heterocyclic compounds and methods of use | 20191219 |
WO-2021088859-A1 | Indazole compound, pharmaceutical composition of same, and applications thereof | 20191106 |
Complexity: | 129 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 134.048012819 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 134.048012819 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 48.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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