5-furan-2-yl-1,3,4-oxadiazol-2-ylamine - CAS 7659-06-5
Catalog: |
BB035625 |
Product Name: |
5-furan-2-yl-1,3,4-oxadiazol-2-ylamine |
CAS: |
7659-06-5 |
Synonyms: |
5-(2-furanyl)-1,3,4-oxadiazol-2-amine; 5-(furan-2-yl)-1,3,4-oxadiazol-2-amine |
IUPAC Name: | 5-(furan-2-yl)-1,3,4-oxadiazol-2-amine |
Description: | 5-Furan-2-yl-1,3,4-oxadiazol-2-ylamine, can be used in the synthesis of various chemical compounds having therapeutic activity, such as N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-2-phenyl-4-quinolinecarboxamide (F863670), a small molecular inhibitor of STAT3, a cancer therapeutic agent against Glioblastoma multiforme tumor cells, and a drug target. |
Molecular Weight: | 151.12 |
Molecular Formula: | C6H5N3O2 |
Canonical SMILES: | C1=COC(=C1)C2=NN=C(O2)N |
InChI: | InChI=1S/C6H5N3O2/c7-6-9-8-5(11-6)4-2-1-3-10-4/h1-3H,(H2,7,9) |
InChI Key: | RNARLYVZVOWYHW-UHFFFAOYSA-N |
Boiling Point: | 318.5 °C at 760 mmHg |
Purity: | 95 % |
Density: | 1.385 g/cm3 |
MDL: | MFCD01710630 |
LogP: | 1.49300 |
GHS Hazard Statement: | H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020196327-A1 | Production method of quinolinecarboxamide derivative or production intermediate thereof | 20190322 |
TW-202102477-A | Quinoline Carboxamide Derivatives and Manufacturing Methods of Manufacturing Intermediates | 20190322 |
JP-2020158498-A | Method for producing quinoline carboxylic acid derivative | 20190322 |
JP-2020158499-A | Manufacturing method of isatin derivative | 20190322 |
JP-2020158500-A | Method for producing 1,3,4-oxa (thia) diazole-2-amine derivative | 20190322 |
Complexity: | 144 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 151.038176411 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 151.038176411 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 78.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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