5-Fluoroisatin - CAS 443-69-6

Catalog:	BB025576
Product Name:	5-Fluoroisatin
CAS:	443-69-6
Synonyms:	5-fluoro-1H-indole-2,3-dione

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	5-fluoro-1H-indole-2,3-dione
Description:	It showed antibacterial and antifungal activities.
Molecular Weight:	165.12
Molecular Formula:	C8H4FNO2
Canonical SMILES:	C1=CC2=C(C=C1F)C(=O)C(=O)N2
InChI:	InChI=1S/C8H4FNO2/c9-4-1-2-6-5(3-4)7(11)8(12)10-6/h1-3H,(H,10,11,12)
InChI Key:	GKODDAXOSGGARJ-UHFFFAOYSA-N
Boiling Point:	417.9 °C at 760 mmHg
Density:	1.446 g/cm³
MDL:	MFCD00022795
LogP:	1.09850

Publication Number	Title	Priority Date
CN-113061098-A	Amide compound and derivative thereof, preparation method, pharmaceutical composition and application	20210118
CN-112538041-A	Bimolecular indole-2, 3-dione derivative and application thereof	20201207
CN-112441989-A	Preparation method and application of flumazenil intermediate 5-fluoroisatoic anhydride	20201116
CN-112321571-A	2-furan-quinoline-4-formamide compound and application thereof	20201027
CN-112079764-A	Synthesis method of sunitinib intermediate 5-fluoroindole-2-ketone	20201012

PMID	Publication Date	Title	Journal
22412623	20120301	5-Fluoro-6'H,7'H,8'H-spiro-[indoline-3,7'-pyrano[3,2-c:5,6-c']di-1-benzopyran]-2,6',8'-trione	Acta crystallographica. Section E, Structure reports online
22346926	20120201	(Z)-2-(5-Fluoro-2-oxoindolin-3-yl-idene)-N-phenyl-hydrazinecarbothio-amide	Acta crystallographica. Section E, Structure reports online
21838297	20110928	Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives	Journal of agricultural and food chemistry
21837201	20110701	5-Fluoro-1-(4-meth-oxy-benz-yl)indoline-2,3-dione	Acta crystallographica. Section E, Structure reports online
21754090	20110401	5''-(4-Chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-5-fluoro-1',1''-dimethyl-indoline-3-spiro-2'-pyrrolidine-3'-spiro-3''-piperidine-2,4''-dione	Acta crystallographica. Section E, Structure reports online

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Fluorinated Building Blocks

[1946823-77-3]
[1,4-Dimethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methanol
[1820736-42-2]
1-{4-[3-(Trifluoromethyl)-1H-pyrazol-1-yl]phenyl}methanamine hydrochloride
[479552-94-8]
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[35989-28-7]
2,5-Dichloro-4-fluorobenzoic acid
[459836-92-1]
3,6-Difluoro-2-methylbenzoic acid
[150517-77-4]
3-Fluoro-5-(trifluoromethyl)benzylamine

Indoles

[1884330-89-5]
1-Methyl-1H-indole-5-D
[2642-37-7]
Indoxyl sulfate potassium salt
[20776-45-8]
5-Benzyloxytryptamine
[109021-59-2]
7-Methoxy-1H-indole-3-carbaldehyde
[467458-46-4]
Ethyl 3-formyl-1H-indole-5-carboxylate
[927181-98-4]
Ethyl 3-formyl-1H-indole-7-carboxylate

Indolines

[2759-12-8]
Indolin-7-amine
[56632-37-2]
Indoline-1-carbothioamide
[32372-82-0]
Isoindoline hydrochloride
[1427475-17-9]
N-(3-Indolinylmethyl)benzylamine
[14204-27-4]
N-(Phenylthio)phthalimide
[1176740-73-0]
5-(2,6-Dimethylphenyl)indoline

Other Pyrimidines

[479552-94-8]
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[451-46-7]
Ethyl 4-fluorobenzoate
[81290-20-2]
Trimethyl(trifluoromethyl)silane
[207605-39-8]
trans-2,3,4,5,6-Pentafluoro-β-nitrostyrene
[1160246-50-3]
2-((4-(P-Tolyl)-6-(trifluoromethyl)pyrimidin-2-yl)oxy)ethanamine
[77776-68-2]
2,4,8-Trichloropyrimido[5,4-d]pyrimidine

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	241
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	165.02260653
Formal Charge:	0
Heavy Atom Count:	12
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	165.02260653
Rotatable Bond Count:	0
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0.7