5-Fluoro-2-hydroxypyrimidine - CAS 2022-78-8
Catalog: |
BB015725 |
Product Name: |
5-Fluoro-2-hydroxypyrimidine |
CAS: |
2022-78-8 |
Synonyms: |
5-fluoro-1H-pyrimidin-2-one |
IUPAC Name: | 5-fluoro-1H-pyrimidin-2-one |
Description: | 5-Fluoro-2-hydroxypyrimidine (CAS# 2022-78-8 ) is a useful research chemical. |
Molecular Weight: | 114.08 |
Molecular Formula: | C4H3FN2O |
Canonical SMILES: | C1=C(C=NC(=O)N1)F |
InChI: | InChI=1S/C4H3FN2O/c5-3-1-6-4(8)7-2-3/h1-2H,(H,6,7,8) |
InChI Key: | HPABFFGQPLJKBP-UHFFFAOYSA-N |
Melting Point: | 170-174 °C |
Purity: | 95 % |
Density: | 1.46 g/cm3 |
Appearance: | Solid |
LogP: | 0.32130 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111269908-A | Preparation of large-space bioreactor based on covalent organic framework material capsule | 20200228 |
CN-111162313-A | Polymer electrolyte and lithium ion battery | 20191223 |
CN-109651452-A | With the active nucleoside phosphorylase long-chain dibasic acid esters analog of suppressing virus replication, preparation method and its medicinal usage | 20181221 |
WO-2020118278-A1 | Compositions and methods for reducing pesticide-induced plant damage and improving plant yield | 20181206 |
EP-3890491-A1 | Compositions and methods for reducing pesticide-induced plant damage and improving plant yield | 20181206 |
PMID | Publication Date | Title | Journal |
22208667 | 20120110 | Role of glutamate 64 in the activation of the prodrug 5-fluorocytosine by yeast cytosine deaminase | Biochemistry |
21583180 | 20090520 | Capecitabine from X-ray powder synchrotron data | Acta crystallographica. Section E, Structure reports online |
18321099 | 20080326 | Guest-induced modification of a magnetically active ultramicroporous, gismondine-like, copper(II) coordination network | Journal of the American Chemical Society |
12003195 | 20020201 | Phase I clinical trial of 5-fluoro-pyrimidinone (5FP), an oral prodrug of 5-fluorouracil (5FU) | Investigational new drugs |
Complexity: | 173 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 114.02294089 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 114.02294089 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 41.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.4 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Fluorinated Building Blocks
Other Pyrimidines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS